The PAH pollution, either directly or indirectly, is strongly affecting the health and well-being of humans, along with other organisms across the planet. The choice of appropriate strategies for PAH remediation is always critical, as it is highly dependent on two major parameters: polluted matrix and environmental conditions. Different remediation methods involving physical, chemical, biological, and lately developed integrated approaches have been continuously applied at varying degree of success. In this work, we discussed the health implications of polycyclic aromatic hydrocarbon.