Silver nanoparticles AgNps are increasingly used in various field, including medical, foood health care’ consumer, wound healing, packaging, textile, cosmetics, electronic, preservation, biolabeling and industrial purpose, due to their unique physical and chemical properties. This paper work is set to examine the silver nanoparticles of mango. The study described an innovative idea of making the best use of waste material. It was concluded that mango leaves are generally discarded as waste into the environment and can be used to synthesized AgNPs which can be therapeutically used to control infection diseases.